The following is an excerpt from MedPage.
Effectiveness of the Pfizer Covid-19 vaccine (Comirnaty) against infection and hospitalization dropped among kids ages 5 to 11 a little over a month after vaccination, according to real-world data from New York during the Omicron wave.
From Dec. 13, 2021 to Jan. 30, 2022, vaccine effectiveness against infection within 2 weeks of full vaccination dropped from 65% (95% CI 62-68) to 12% (95% CI 8-16) by 28 to 34 days, reported Vajeera Dorabawila, PhD, of the New York State Department of Health, and colleagues.
Moreover, vaccine effectiveness against hospitalization dropped from 100%, albeit with a wide confidence interval (95% CI -189 to 100), to 48% (95% CI -12 to 75), they noted in a study published on the preprint server medRxiv.
The authors hypothesized that the lower dose among kids ages 5 to 11 accounted for the "markedly lower" vaccine effectiveness against infection. The younger group's two-dose primary series consists of 10 μg apiece versus 30 μg apiece for the older group. (continued)
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