(STUDY) Pfizer’s mRNA Covid shot can cause ‘off-target’ immune responses


The following is from The Vaccine Reaction.

A new study by published in the journal Nature last week revealed that the mRNA (messenger ribonucleic acid) Covid-19 gene therapies can unexpectedly cause cells of the body to misread the mRNA coding and produce unintended proteins (also known as ribosomes), a process described in the study as “frameshifting.”

The study by the Medical Research Council (MRC) Toxicology Unit at Cambridge University in England found that “bases with a chemical modification called N1-methylpseudouridine, which are currently contained in mRNA therapies,” are behind these misreads or “slips” along the mRNA sequence.

One-Third of Vaccinated Individuals Experienced “Off-Target” Immune Responses

The study, which involved lab work on Pfizer/BioNTech’s Comirnaty shot in mice and subsequently on 21 people, found that about one-third of the vaccinated individuals experienced unintended immune responses. Researchers reportedly “identified the sequence within the mRNA that causes this to occur and found a way to prevent ‘off-target’ immune responses.”

The study shows that the use of modified nucleotides (the building blocks of RNA) to produce the mRNA Covid shots can cause the “cellular machinery that reads the recipe for the mRNA to make proteins to slow down, pause, and then start reading again, but beginning from a slightly different point in the recipe,” according to Stephen Griffin, PhD, professor of cancer virology at Cambridge University. This means that, in addition to the “main vaccine-driven immune response against the spike protein, other minor responses can also arise targeting the new protein sequences.”

“The messenger RNA vaccines contain short strands of genetic code that provide the instructions for the cells in our bodies to make copies of the spike protein on the surface of the coronavirus that causes Covid-19, said Neil Mabbott, PhD, who heads the immunology division of The Roslin Institute and Royal School of Veterinary Sciences at the University of Edinburgh in Scotland. “These proteins are then used to train our immune systems to recognize and destroy the virus should we become infected with it.

Dr. Mabbott described the ability of mRNA shots to sometimes trigger a “process known as frameshift,” which can cause cells to misread the gene therapy’s mRNA, which can then create abnormal versions of the coronavirus spike protein being made.

Scientists Maintain mRNA Misreads Do Not Make Covid Shots Harmful

But Dr. Mabbott suggested that the ribosome misreads identified in the study should be of no concern in terms of the safety or effectiveness of mRNA Covid shots. He said:

The findings in this study do not suggest that these frameshift mistakes are harmful to the body, nor do they suggest they are associated with the very rare adverse reactions to the vaccines that some people have experience such as myocarditis. By showing how these frameshift mistakes can prevented this provides an excellent opportunity to increase the efficacy of the mRNA vaccines and further improve their safety profile.(Continued…)

Read more here.

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12 thoughts on “(STUDY) Pfizer’s mRNA Covid shot can cause ‘off-target’ immune responses”

    1. I wish I had never taken the vaccine shot also. My daughter told me to wait; it was experimental. I thought if we took the vaccine, we could then lead a normal life. Had I had known that we were going to be imprisoned in our own homes, I certainly did not need the vaccine. Why did I need the vaccine if I was mostly home?

      My daughter moved her whole family to Florida since that state did not require vaccines nor students being masked. It was the student’s choice to wear or not wear a mask. My daughter and her two children were never vaccinated. She and her daughter have not caught Covid. Her son had Covid and recuperated within five days.
      So many vaccinated people that we know are dealing with health issues, some of them auto immune issues.
      I ended in the Emergency Hospital after three days of getting the second Pfizer vaccine due to the worse Urinary Infection I’ve ever had in my life. I had not had an infection for 25 years. I also had other side effects which lasted for six months.
      A crime against humanity was committed by these scientists who went looking in caves for bats. When is the truth going to be exposed and people held responsible for these crimes?

    2. I wish I had never taken the vaccine shot also. My daughter told me to wait; it was experimental. I thought if we took the vaccine, we could then lead a normal life. Had I had known that we were going to be imprisoned in our own homes, I certainly did not need the vaccine. Why did I need the vaccine if I was mostly home?

      My daughter moved her whole family to Florida since that state did not require vaccines nor students being masked. It was the student’s choice to wear or not wear a mask. My daughter and her two children were never vaccinated. She and her daughter have not caught Covid. Her son had Covid and recuperated within five days.
      So many vaccinated people that we know are dealing with health issues, some of them auto immune issues.
      I ended in the Emergency Hospital after three days of getting the second Pfizer vaccine due to the worse Urinary Infection I’ve ever had in my life. I had not had an infection for 25 years. I also had other side effects which lasted for six months.
      A crime against humanity was committed by these scientists who went looking in caves for bats. When is the truth going to be exposed and people held responsible for these crimes?

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