The following is from MedPage Today.
Two Yale University researchers want to understand why symptoms that emerge rarely after Covid-19 vaccines occur.
Persistent symptoms after vaccination -- sometimes called "long vax" -- are similar to those reported with long Covid, including small-fiber neuropathy and postural orthostatic tachycardia syndrome (POTS).
But studies have largely shown that the risk of post-vaccine events do not exceed background rates, or that the odds of a new diagnosis like POTS are greater after SARS-CoV-2 infection than after vaccination.
Akiko Iwasaki, PhD, and Harlan Krumholz, MD, SM, both of Yale University in New Haven, Connecticut, recently expanded their ongoing LISTEN study of long COVID to include people with adverse events after Covid shots, hoping to match abnormal post-vaccine symptoms with corresponding immune responses.
LISTEN participants self-report symptoms and other data through questionnaires. Some individuals are asked to give blood and saliva samples, either at home or at a local testing center, as part of the study.
"We were developing the LISTEN study to better characterize long Covid using clinical, patient-generated, and patient-reported information and, for a subset, to conduct deep immunophenotyping," Krumholz told MedPage Today.
"Around that time, we also became aware that there were people who were reporting a chronic syndrome, with many similar symptoms after receiving vaccination," he said. "These people were not political and not anti-vaccination -- they had all been vaccinated -- but seemed to have symptoms that were persistent and debilitating."
Both groups of people felt dismissed by clinicians because conventional testing failed to identify a cause, Krumholz noted. "Those with post-vaccination syndrome also encountered some cruel responses, as their experience was used by others to further political agendas on all sides," he said. (Continued...)
Link to article here.